Described herein are quinazoline-based compounds and formulations thereof. In some embodiments, the compounds and/or formulations thereof can be effective to inhibit and/or kill A. baumannii. Also described herein are methods of treating a subject in need thereof by administering to the subject in need thereof a quinazoline-based compound and/or formulation thereof to the subject in need thereof.
Manetsch, Roman; Van Horn, Kurt S.; Burda, Whittney; Shaw, Lindsey N.; Fleeman, Renee; Barber, Megan; and Flanigan, David Lawrence, "N2N N4-disubstituted quinazoline-2,4-diamines and uses thereof" (2019). USF Patents. 998.
University of South Florida