A method of making a model test system in guinea pigs for leiomyomas and early stage atherosclerosis by ovariectomizing young female guinea pigs, and co-implanting a continuous slow release device for releasing an estrogenic compound or analog thereof and a retinoid compound or analogs thereof.
Tsibris, John C. M. and Porter, Kathy B., "Guinea pig model for leiomyomas" (2001). USF Patents. 805.
University of South Florida