Disclosed herein are ester-bond containing tea polyphenols that has a susceptibility to nucleophilic attack, their analogs and pharmaceutically acceptable salts, method for inhibiting proteasomal chymotrypsin-like activity in vivo and in vitro, methods for cancer treatment with tea-derived polyphenols, such as EGCG, ECG, GCG, or CG, as well as pharmaceutical compositions comprising the same.
Dou, Q. Ping; Nam, Sangkil; and Smith, David M., "Tea polyphenol esters and analogs thereof for cancer prevention and treatment" (2004). USF Patents. 750.
University of South Florida