Tea polyphenol esters and analogs thereof for cancer prevention and treatment

Authors

Q. Ping Dou
Sangkil Nam
David M. Smith

Document Type

Patent

Publication Date

March 2004

Patent Number

6713506

Abstract

Disclosed herein are ester-bond containing tea polyphenols that has a susceptibility to nucleophilic attack, their analogs and pharmaceutically acceptable salts, method for inhibiting proteasomal chymotrypsin-like activity in vivo and in vitro, methods for cancer treatment with tea-derived polyphenols, such as EGCG, ECG, GCG, or CG, as well as pharmaceutical compositions comprising the same.

Application Number

09/973,834

Recommended Citation

Dou, Q. Ping; Nam, Sangkil; and Smith, David M., "Tea polyphenol esters and analogs thereof for cancer prevention and treatment" (2004). USF Patents. 750.
https://digitalcommons.usf.edu/usf_patents/750

Assignees

University of South Florida

Filing Date

10/11/2001

Primary/U.S. Class

514/450