Document Type

Patent

Publication Date

January 2007

Patent Number

7157419

Abstract

Growth factor binding molecules having a plurality of peptide loops attached to a non-peptide organic scaffold, preferably having pseudo-six amino acid peptide loops with four amino acid sidechains. The growth factor binding molecules specifically bind various growth factors and are suitable for treating a subject having tumors or restinosis. In one embodiment a platelet-derived growth factor binding molecule is disclosed that is used to inhibit tumor growth and angiogenesis in solid tumors.

Application Number

09/811,945

Assignees

University of South Florida

Filing Date

03/21/2001

Primary/U.S. Class

514/2

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