A compound or groups of compounds, present in an active principle, derived from tunicates of the species Synoicum adareanum, as well as to pharmaceutical compositions comprising these compounds. Extracts from tunicates show selective toxicity against several different cancer cell lines in the NCI 60 cell line panel. These compounds are useful in the effective treatment of cancers, particularly malignant melanomas, colon cancer, and renal cancer cell lines.
Baker, Bill J.; Diyabalanage, Thusahara; McClintock, James B.; and Amsler, Charles D., "Cytotoxin compound and method of isolation" (2009). USF Patents. 578.
University of South Florida