There is provided a method of modulating the function of a transcription factor by administering an effective amount of an oligonucleotide containing optimal nucleotide binding site for the transcription factor. A therapeutic agent having an effective amount of an oligonucleotide for modulating function of a transcription factor and a pharmaceutically acceptable carrier is also provided. Also provided is a treatment of patients having illnesses in which the activation of transcription factors plays a role by administering to a patient an effective amount of an oligonucleotide which competitively binds the related transcription factor.
Zuckerman, Kenneth S. and Liu, Richard Y., "Method for the modulation of function of transcription factors" (2009). USF Patents. 553.
University of South Florida