A method of increasing megakaryocytes and platelet numbers in a patient comprising the step of inhibiting SHIP expression, including SHIP's enzymatic activity and signaling functions, whereby normal blood clotting is induced.
Kerr, William G.; Desponts, Caroline; and Perez, Lia Elena, "SHIP-deficiency to increase megakaryocyte progenitor production" (2010). USF Patents. 524.
University of South Florida