Document Type
Patent
Publication Date
June 2011
Patent Number
7956193
Abstract
Cobalt (II) complexes of porphyrins are effective catalysts for intramolecular nitrene insertion of C—H bonds with arylsulfonyl azides. The cobalt-catalyzed process can proceed efficiently under mild and neutral conditions in low catalyst loading without the need of other reagents or additives, generating nitrogen gas as the only byproduct. Using the simple tetraphenylporphyrin (TPP) as the ligand, the cobalt-catalyzed intramolecular amidation can be applied to primary, secondary, and tertiary C—H bonds and suitable for a broad range of arylsulfonyl azides, leading to the syntheses of various benzosultam derivatives in excellent yields
Application Number
12/151,182
Recommended Citation
Zhang, X. Peter and Ruppel, Joshua V., "Intramolecular C-H amination with sulfonyl azides" (2011). USF Patents. 404.
https://digitalcommons.usf.edu/usf_patents/404
Assignees
University of South Florida
Filing Date
05/05/2008
Primary/U.S. Class
548/207
