A classifier to predict cellular radiation sensitivity based on gene expression profiles in thirty-five cell lines from the NCI panel of 60 cancer cell lines (NCI-60), using a novel approach to predictive gene analysis. Three novel genes are provided, retinoblastoma binding protein 4 (RbAp48), G-protein signaling regulator 19 (RGS19) and ribose-5-phosphate isomerase A (R5PIA) whose expression values were correlated with radiation sensitivity.
Torres-Roca, Javier F.; Yeatman, Timothy; and Eschrich, Steven, "Identification of novel targets for radio sensitization using a genomic-based radiation sensitivity classifier" (2011). USF Patents. 373.
H. Lee Moffitt Cancer Center and Research Institute, Inc.