A61K 2300/00, A61K 31/496, A61P 35/00
Disclosed herein are compositions and methods for treating cancer. Further provided herein are compositions and methods for reducing, inhibiting, or preventing resistance of cancer to tyrosine kinase inhibitors. The methods may include administering an anti-resistance agent such as a CYP51A1 inhibitor or an agonist of miRNA-764 (SEQ ID NO: 4) to a subject. A tyrosine kinase inhibitor may also be administered to the subject in addition to the anti-resistance agent.
Mohapatra, Subhra; Mohapatra, Shyam S.; Howell, Mark; and Nair, Rajesh, "Methods and compositions for treating drug resistance in cancer" (2020). USF Patents. 1205.
TRANSGENEX NANOBIOTECH, INC.