A61K 31/40, A61K 31/357, A61P 35/02
The present invention relates to a composition including an inhibitor against the function of an Mi-2/NuRD chromatin remodeling complex for inhibiting metastasis and preventing and treating cancer diseases, and more particularly, the composition may inhibit the MBD2-p66Î± (GATAD2A) interaction by means of the Mi-2/NuRD CRC function inhibitor, and thus is expected to be effectively used as a composition capable of inhibiting metastasis and preventing and treating cancer diseases.
Kim, Chul Geun; Kim, Min Young; Lim, Young Su; Ha, Dae Hyun; Lee, Young Yiul; Ryu, Buom Yong; Uversky, Vladimir; Na, Insung; Chen, Yu; and van der Vaart, Arjan, "Composition comprising compound inhibiting interactions of MBD2 and P66Î± for anti-metastasis and prevention and treatment of cancer disease" (2020). USF Patents. 1143.
Industry-University Cooperation Foundation Hanyang University; University of South Florida