Document Type

Article

Publication Date

September 2018

Patent Number

10080725

CPC

A61K 31/105, A61K 31/145, A61K 33/04, C07C 2101/14, C07C 321/14, C07C 321/20, C07C 381/00, C07C 321/02, C07C 2601/14, C07H 15/00

Abstract

Synthetically-derived S,S-heterodisubstituted disulfides that exhibit potent in vitro antibacterial activity against a variety of bacteria, including Staphylococcus aureus, methicillin-resistant Staphylococcus aureus and Francisella tularensis. The present invention provides compounds, methods and compositions effective to treat microbial/bacterial infections, and, especially, infections arising from bacteria which have developed resistance to conventional antibiotics.

Application Number

15/349475

Assignees

University of South Florida

Filing Date

11/11/2016

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