Presentation Type

Poster

What's New? A Study of Novelty P3 Stability.

Abstract

The stability of a brain response (Event Related Potential, or ERP) is investigated to determine the change in amplitude occurring within an individual after repeated elicitations of the brain component. This ERP component, the Novelty P3, is known to be elicited in response to task irrelevant, novel events. Testing the repeatability of the Novelty P3 over time indicates whether the component can continue to be elicited if the stimulus is no longer novel to the individual. Participants complete the same task four times weekly. The task is designed as an auditory oddball paradigm in which participants are asked to distinguish between two relevant stimuli (tones). One of the task relevant tones is presented a greater number of times than the second task relevant tone. An unexpected, irrelevant sound is infrequently intermixed to elicit the Novelty P3. The infrequent task relevant tone elicits a second ERP component known as the P300. The P300 has been established to have amplitude stability within individuals after repeated stimulus exposure, and has been used to develop applications such as the P300 Brain Computer Interface (BCI). The Novelty P3 will be applied to assess sub-concussive brain injury, if found to have good within subject stability.

Categories

Behavioral Sciences

Research Type

Research Assistant

Mentor Information

Dr. Yael Arbel

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What's New? A Study of Novelty P3 Stability.

The stability of a brain response (Event Related Potential, or ERP) is investigated to determine the change in amplitude occurring within an individual after repeated elicitations of the brain component. This ERP component, the Novelty P3, is known to be elicited in response to task irrelevant, novel events. Testing the repeatability of the Novelty P3 over time indicates whether the component can continue to be elicited if the stimulus is no longer novel to the individual. Participants complete the same task four times weekly. The task is designed as an auditory oddball paradigm in which participants are asked to distinguish between two relevant stimuli (tones). One of the task relevant tones is presented a greater number of times than the second task relevant tone. An unexpected, irrelevant sound is infrequently intermixed to elicit the Novelty P3. The infrequent task relevant tone elicits a second ERP component known as the P300. The P300 has been established to have amplitude stability within individuals after repeated stimulus exposure, and has been used to develop applications such as the P300 Brain Computer Interface (BCI). The Novelty P3 will be applied to assess sub-concussive brain injury, if found to have good within subject stability.