Title

Quality of Life in Obsessive-Compulsive Disorder: The Role of Mediating Variables

Document Type

Article

Publication Date

2014

Keywords

Quality of life, Obsessive-compulsive disorder, Treatment, Assessment, Depression, Anxiety

Digital Object Identifier (DOI)

https://doi.org/10.1016/j.psychres.2012.10.006

Abstract

This study examined the association of various clinical features of obsessive-compulsive disorder (OCD) with quality of life (QoL) in 102 adults with a principal diagnosis of OCD. Participants were assessed by trained clinicians using the Anxiety Disorders Interview Schedule 4th edition, the Yale-Brown Obsessive-Compulsive Scale, and an unstructured clinical interview. Subjects completed the MOS-36 Item Short Form Health Survey, and Beck Depression Inventory-II. Obsessive-compulsive symptom severity was negatively correlated with emotional health, social functioning and general health QoL. Depressive symptoms mediated the relationship between obsessive-compulsive symptom severity and emotional health, social functioning and general health QoL. Additionally, interference of obsessive-compulsive symptoms mediated the relationship between obsessive-compulsive symptom severity and emotional health, social functioning and general health QoL. Resistance against obsessive-compulsive symptoms mediated the relationship between obsessive-compulsive symptom severity and social functioning QoL. Diminished QoL is present in persons with OCD and is essential in understanding the complete clinical picture of OCD.

Was this content written or created while at USF?

Yes

Citation / Publisher Attribution

Psychiatry Research, v. 206, issue 1, p. 43-49

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