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Submissions from 2020

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Role of Neutrophils in Ischemic Heart Failure, Vasundhara Kain and Ganesh V. Halade

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Resolvin E1 Derived from Eicosapentaenoic Acid Prevents Hyperinsulinemia and Hyperglycemia in a Host Genetic Manner, Anandita Pal, Abrar E. Al-Shaer, William Guesdon, Maria J. Torres, Michael Armstrong, Kevin Quinn, Traci Davis, Nichole Reisdorph, P. Darrell Neufer, Espen E. Spangenburg, Ian Carroll, Richard P. Bazinet, Ganesh V. Halade, Joan Clària, and Saame Raza Shaikh

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Molecular and Cellular Differences in Cardiac Repair of Male and Female Mice, Amanda B. Pullen, Vasundhara Kain, Charles N. Serhan, and Ganesh V. Halade

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Lack of Resolution Sensor Drives Age-Related Cardiometabolic and Cardiorenal Defects and Impedes Inflammation-Resolution in Heart Failure, Bochra Tourki, Vasundhara Kain, Amanda B. Pullen, Paul C. Norris, Nirav Patel, Pankaj Arora, Xavier Leroy, Charles N. Serhan, and Ganesh V. Halade

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Deficit of Resolution Receptor Magnifies Inflammatory Leukocyte directed Cardiorenal and Endothelial Dysfunction with Signs of Cardiomyopathy of Obesity, Bochra Tourki, Vasundhara Kain, Saame Raza Shaikh, Xavier Leroy, Charles N. Serhan, and Ganesh V. Halade

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Progressive Cardiac Arrhythmias and Ecg Abnormalities in the Huntington'S Disease Bachd Mouse Model, Yujie Zhu, Isaac Shamblin, Efrain Rodriguez, Grace E. Salzer, Lita Araysi, Katherine A. Margolies, Ganesh V. Halade, Silvio H. Litovsky, Steven Pogwizd, Michelle Gray, and Sabine Huke

Submissions from 2019

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Bone Benefits of Fish Oil Supplementation Depend on Its Epa and Dha Content, Haissam Abou-Saleh, Allal Ouhtit, Ganesh V. Halade, and Md Mizanur Rahman

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Risk of Major Adverse Cardiovascular Events and Major Hemorrhage Among White and Black Patients Undergoing Percutaneous Coronary Intervention, Anping Cai, Chrisly Dillon, William B. Hillegass, Mark Beasley, Brigitta C. Brott, Vera A. Bittner, Gilbert J. Perry, Ganesh V. Halade, Sumanth D. Prabhu, and Nita A. Limdi

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Mitoquinone Ameliorates Pressure Overload-Induced Cardiac Fibrosis and Left Ventricular Dysfunction in Mice, Kah Yong Goh, Li He, Jiajia Song, Miki Jinno, Aaron J. Rogers, Palaniappan Sethu, Ganesh Halade, Rajasekaran N. Soorappan, Xiaoguang Liu, Sumanth D. Prabhu, Victor Darley-Usmar, Adam R. Wende, and Lufang Zhou

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Lipoxygenase Drives Lipidomic and Metabolic Reprogramming in Ischemic Heart Failure, Ganesh V. Halade, Vasundhara Kain, Bochra Tourki, and Jeevan Kumar Jadapalli

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Specialized Pro-Resolving Mediators Directs Cardiac Healing and Repair with Activation of Inflammation and Resolution Program in Heart Failure, Ganesh V. Halade and Bochra Tourki

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Adaptive Immunity-Driven Inflammation and Cardiovascular Disease, Daria V. Ilatovskaya, Ganesh V. Halade, and Kristine Y. DeLeon-Pennell

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Immune Responsive Resolvin D1 Programs Peritoneal Macrophages and Cardiac Fibroblast Phenotypes in Diversified Metabolic Microenvironment, Vasundhara Kain and Ganesh V. Halade

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Inhibition of Fpr2 Impaired Leukocytes Recruitment and Elicited Non-Resolving Inflammation in Acute Heart Failure, Vasundhara Kain, Jeevan Kumar Jadapalli, Bochra Tourki, and Ganesh V. Halade

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Obesogenic Diet in Aging Mice Disrupts Gut Microbe Composition and Alters Neutrophi:Lymphocyte Ratio, Leading to Inflamed Milieu in Acute Heart Failure, Vasundhara Kain, William Van Der Pol, Nithya Mariappan, Aftab Ahmad, Peter Eipers, Deanna L. Gibson, Cecile Gladine, Claire Vigor, Thierry Durand, Casey Morrow, and Ganesh V. Halade

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Temperature-Responsive Polymersomes of Poly(3-Methyl- N-Vinylcaprolactam)- Block-Poly(N-Vinylpyrrolidone) to Decrease Doxorubicin-Induced Cardiotoxicity, Veronika Kozlovskaya, Fei Liu, Yiming Yang, Kevin Ingle, Shuo Qian, Ganesh V. Halade, Volker S. Urban, and Eugenia Kharlampieva

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Pretreatment of Carprofen Impaired Initiation of Inflammatory- and Overlapping Resolution Response and Promoted Cardiorenal Syndrome in Heart Failure, Veena Krishnan, David Booker, Gabrielle Cunningham, Jeevan Kumar Jadapalli, Vasundhara Kain, Amanda B. Pullen, and Ganesh V. Halade

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Race, Natriuretic Peptides, and High-Carbohydrate Challenge: a Clinical Trial, Nirav Patel, Griffin K. Russell, Kiran Musunuru, Orlando M. Gutierrez, Ganesh Halade, Vasundhara Kain, Wenjian Lv, Sumanth D. Prabhu, Kenneth B. Margulies, Thomas P. Cappola, Garima Arora, Thomas J. Wang, and Pankaj Arora

Submissions from 2018

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The Mouse Heart Attack Research Tool 1.0 Database, Kristine Y. Deleon-Pennell, Rugmani Padmanabhan Iyer, Yonggang Ma, Andriy Yabluchanskiy, Rogelio Zamilpa, Ying Ann Chiao, Presley L. Cannon, Abdullah Kaplan, Courtney A. Cates, Elizabeth R. Flynn, Ganesh V. Halade, Lisandra E. de Castro Brás, and Merry L. Lindsey

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Paradigm Shift – Metabolic Transformation of Docosahexaenoic and Eicosapentaenoic Acids to Bioactives Exemplify the Promise of Fatty Acid Drug Discovery, Ganesh V. Halade, Laurence M. Black, and Mahendra Kumar Verma

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Comprehensive Targeted and Non-Targeted Lipidomics Analyses in Failing and Non-Failing Heart, Ganesh V. Halade, Anela Dorbane, Kevin A. Ingle, Vasundhara Kain, Jean Marie Schmitter, and Boutayna Rhourri-Frih

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Heart Functional and Structural Compendium of Cardiosplenic and Cardiorenal Networks in Acute and Chronic Heart Failure Pathology, Ganesh V. Halade, Vasundhara Kain, and Kevin A. Ingle

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Immune Responsive Resolvin D1 Programs Myocardial Infarction–Induced Cardiorenal Syndrome in Heart Failure, Ganesh V. Halade, Vasundhara Kain, and Charles N. Serhan

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Subacute Treatment of Carprofen Facilitate Splenocardiac Resolution Deficit in Cardiac Injury, Ganesh V. Halade, Vasundhara Kain, Griffin M. Wright, and Jeevan Kumar Jadapalli

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Splenic Leukocytes Define the Resolution of Inflammation in Heart Failure, Ganesh V. Halade, Paul C. Norris, Vasundhara Kain, Charles N. Serhan, and Kevin A. Ingle

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Unified Nexus of Macrophages and Maresins in Cardiac Reparative Mechanisms, Jeevan Kumar Jadapalli and Ganesh V. Halade

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Cancer Therapy-Induced Cardiovascular Toxicity: Doxorubicin Triggers Splenic Contraction and Irreversible Dysregulation of Cox and Lox that Alters the Inflammation-Resolution Program in the Myocardium, Jeevan Kumar Jadapalli, Griffin W. Wright, Vasundhara Kain, Mohammad Asif Sherwani, Ravi Sonkar, Nabiha Yusuf, and Ganesh V. Halade

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Genetic Deletion of 12/15 Lipoxygenase Promotes Effective Resolution of Inflammation Following Myocardial Infarction, Vasundhara Kain, Kevin A. Ingle, Janusz Kabarowski, Stephen Barnes, Nita A. Limdi, Sumanth D. Prabhu, and Ganesh V. Halade

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Excess Ω-6 Fatty Acids Influx in Aging Drives Metabolic Dysregulation, Electrocardiographic Alterations, and Low-Grade Chronic Inflammation, Vasundhara Kain, Kevin A. Ingle, Maureen Kachman, Heidi Baum, Gobinath Shanmugam, Namakkal S. Rajasekaran, Martin E. Young, and Ganesh V. Halade

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Nox2 Activity is Required in Obesity-Mediated Alteration of Bone Remodeling, Md Mizanur Rahman, Amina El Jamali, Ganesh V. Halade, Allal Ouhtit, Haissam Abou-Saleh, and Gianfranco Pintus

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The Failing of the Obesity Paradox in the Failing Heart, Bochra Tourki and Ganesh V. Halade

Submissions from 2017

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Obesity and Cardiometabolic Defects in Heart Failure Pathology, Ganesh V. Halade and Vasundhara Kain

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Interaction of 12/15-Lipoxygenase with Fatty Acids Alters the Leukocyte Kinetics Leading to Improved Postmyocardial Infarction Healing, Ganesh V. Halade, Vasundhara Kain, Kevin A. Ingle, and Sumanth D. Prabhu

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Metabolic and Biochemical Stressors in Diabetic Cardiomyopathy, Vasundhara Kain and Ganesh V. Halade

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Resolution Agonist 15-Epi-Lipoxin A4 Programs Early Activation of Resolving Phase in Post-Myocardial Infarction Healing, Vasundhara Kain, Fei Liu, Veronika Kozlovskaya, Kevin A. Ingle, Subhashini Bolisetty, Anupam Agarwal, Santosh Khedkar, Sumanth D. Prabhu, Eugenia Kharlampieva, and Ganesh V. Halade

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Leukocyte Diversity in Resolving and Nonresolving Mechanisms of Cardiac Remodeling, Bochra Tourki and Ganesh Halade

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Glucose Transporter 4-Deficient Hearts Develop Maladaptive Hypertrophy in Response to Physiological or Pathological Stresses, Adam R. Wende, Jaetaek Kim, William L. Holland, Benjamin E. Wayment, Brian T. O’Neill, Joseph Tuinei, Manoja K. Brahma, Mark E. Pepin, Mark A. McCrory, Ivan Luptak, Ganesh V. Halade, Sheldon E. Litwin, and E. Dale Abel

Submissions from 2016

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Cd36 is a Matrix Metalloproteinase-9 Substrate that Stimulates Neutrophil Apoptosis and Removal during Cardiac Remodeling, Kristine Y. Deleon-Pennell, Yuan Tian, Bai Zhang, Courtney A. Cates, Rugmani Padmanabhan Iyer, Presley Cannon, Punit Shah, Paul Aiyetan, Ganesh V. Halade, Yonggang Ma, Elizabeth Flynn, Zhen Zhang, Yu Fang Jin, Hui Zhang, and Merry L. Lindsey

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Aging Dysregulates D- and E-Series Resolvins to Modulate Cardiosplenic and Cardiorenal Network Following Myocardial Infarction, Ganesh V. Halade, Vasundhara Kain, Laurence M. Black, Sumanth D. Prabhu, and Kevin A. Ingle

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Neutrophils: Friend, Foe, or Contextual Ally in Myocardial Healing, Ganesh V. Halade and Yonggang Ma

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Abrogation of Nrf2 Impairs Antioxidant Signaling and Promotes Atrial Hypertrophy in Response to High-Intensity Exercise Stress, Radhakrishnan Rajesh Kumar, Madhusudhanan Narasimhan, Gobinath Shanmugam, Jennifer Hong, Asokan Devarajan, Sethu Palaniappan, Jianhua Zhang, Ganesh V. Halade, Victor M. Darley-Usmar, John R. Hoidal, and Namakkal S. Rajasekaran

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Myocardial Infarction Superimposed on Aging: Mmp-9 Deletion Promotes M2 Macrophage Polarization, Andriy Yabluchanskiy, Yonggang Ma, Kristine Y. Deleon-Pennell, Raffaele Altara, Ganesh V. Halade, Andrew P. Voorhees, Nguyen T. Nguyen, Yu Fang Jin, Michael D. Winniford, Michael E. Hall, Hai Chao Han, and Merry L. Lindsey

Submissions from 2015

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Cardiomyocyte-Specific Bmal1 Deletion in Mice Triggers Diastolic Dysfunction, Extracellular Matrix Response, and Impaired Resolution of Inflammation, Kevin A. Ingle, Vasundhara Kain, Mehak Goel, Sumanth D. Prabhu, Martin E. Young, and Ganesh V. Halade

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Big Eater Macrophages Dominate Inflammation Resolution Following Myocardial Infarction, Vasundhara Kain and Ganesh V. Halade

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Resolvin D1 Activates the Inflammation Resolving Response at Splenic and Ventricular Site Following Myocardial Infarction Leading to Improved Ventricular Function, Vasundhara Kain, Kevin A. Ingle, Romain A. Colas, Jesmond Dalli, Sumanth D. Prabhu, Charles N. Serhan, Medha Joshi, and Ganesh V. Halade

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Obesity Superimposed on Aging Magnifies Inflammation and Delays the Resolving Response after Myocardial Infarction, Elizabeth F. Lopez, Janusz H. Kabarowski, Kevin A. Ingle, Vasundhara Kain, Stephen Barnes, David K. Crossman, Merry L. Lindsey, and Ganesh V. Halade

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Building a Better Infarct: Modulation of Collagen Cross-Linking to Increase Infarct Stiffness and Reduce Left Ventricular Dilation Post-Myocardial Infarction, Andrew P. Voorhees, Kristine Y. DeLeon-Pennell, Yonggang Ma, Ganesh V. Halade, Andriy Yabluchanskiy, Rugmani Padmanabhan Iyer, Elizabeth Flynn, Courtney A. Cates, Merry L. Lindsey, and Hai Chao Han

Submissions from 2014

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Aging and Energetics' 'Top 40' Future Research Opportunities 2010-2013, Steven N. Austad, David B. Allison, Lisa H. Antoine, Scott W. Ballinger, Marcas M. Bamman, Peggy Biga, Victor M. Darley-Usmar, Gordon Fisher, Julia M. Gohlke, Ganesh V. Halade, John L. Hartman, Gary R. Hunter, Joseph L. Messina, Tim R. Nagy, Eric P. Plaisance, Mickie L. Powell, Kevin A. Roth, Michael W. Sandel, Tonia S. Schwartz, Daniel L. Smith, J. David Sweatt, Trygve O. Tollefsbol, Stephen A. Watts, Yongbin Yang, and Jianhua Zhang

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Streptococcus Pneumoniae Translocates into the Myocardium and Forms Unique Microlesions that Disrupt Cardiac Function, Armand O. Brown, Beth Mann, Geli Gao, Jane S. Hankins, Jessica Humann, Jonathan Giardina, Paola Faverio, Marcos I. Restrepo, Ganesh V. Halade, Eric M. Mortensen, Merry L. Lindsey, Martha Hanes, Kyle I. Happel, Steve Nelson, Gregory J. Bagby, Jose A. Lorent, Pablo Cardinal, Rosario Granados, Andres Esteban, Claude J. LeSaux, Elaine I. Tuomanen, and Carlos J. Orihuela

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Citrate Synthase is a Novel in Vivo Matrix Metalloproteinase-9 Substrate that Regulates Mitochondrial Function in the Postmyocardial Infarction Left Ventricle, Lisandra E. De Castro Brás, Courtney A. Cates, Kristine Y. DeLeon-Pennell, Yonggang Ma, Rugmani Padmanabhan Iyer, Ganesh V. Halade, Andriy Yabluchanskiy, Gregg B. Fields, Susan T. Weintraub, and Merry L. Lindsey

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Inflammation Revisited: Inflammation Versus Resolution of Inflammation Following Myocardial Infarction, Vasundhara Kain, Sumanth D. Prabhu, and Ganesh V. Halade

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Caveolin-1 Deletion Exacerbates Cardiac Interstitial Fibrosis by Promoting M2 Macrophage Activation in Mice after Myocardial Infarction, Pooja Shivshankar, Ganesh V. Halade, Cheresa Calhoun, Gladys P. Escobar, Ali J. Mehr, Fabio Jimenez, Cindy Martinez, Harshita Bhatnagar, Corey H. Mjaatvedt, Merry L. Lindsey, and Claude Jourdan Le Saux

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Cardiac Extracellular Proteome Profiling and Membrane Topology Analysis Using Glycoproteomics, Yuan Tian, Tejaswi Koganti, Zhihao Yao, Presley Cannon, Punit Shah, Laura Pietrovito, Alessandra Modesti, Paul Aiyetan, Kristine Deleon-Pennell, Yonggang Ma, Ganesh V. Halade, Chindo Hicks, Hui Zhang, and Merry L. Lindsey

Submissions from 2013

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Texas 3-Step Decellularization Protocol: Looking at the Cardiac Extracellular Matrix, Lisandra E. De Castro Brás, Trevi A. Ramirez, Kristine Y. DeLeon-Pennell, Ying Ann Chiao, Yonggang Ma, Qiuxia Dai, Ganesh V. Halade, Kevin Hakala, Susan T. Weintraub, and Merry L. Lindsey

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Extracellular Matrix Biomarkers of Adverse Remodeling after Myocardial Infarction, Kristine Y. DeLeon, Lisandra E.de Brás, Yonggang Ma, Ganesh V. Halade, Jianhua Zhang, and Merry L. Lindsey

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Matrix Metalloproteinase (Mmp)-9: a Proximal Biomarker for Cardiac Remodeling and a Distal Biomarker for Inflammation, Ganesh V. Halade, Yu Fang Jin, and Merry L. Lindsey

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Reduced Bdnf Attenuates Inflammation and Angiogenesis to Improve Survival and Cardiac Function Following Myocardial Infarction in Mice, Ganesh V. Halade, Yonggang Ma, Trevi A. Ramirez, Jianhua Zhang, Qiuxia Dai, Julie G. Hensler, Elizabeth F. Lopez, Omid Ghasemi, Yu Fang Jin, and Merry L. Lindsey

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Concentrated Fish Oil (Lovaza®) Extends Lifespan and Attenuates Kidney Disease in Lupus-Prone Short-Lived (Nzbxnzw)F1 Mice, Ganesh V. Halade, Paul J. Williams, Jyothi M. Veigas, Jeffrey L. Barnes, and Gabriel Fernandes

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Obese and Diabetic Kkay Mice Show Increased Mortality but Improved Cardiac Function Following Myocardial Infarction, James R. Heaberlin, Yonggang Ma, Jianhua Zhang, Seema S. Ahuja, Merry L. Lindsey, and Ganesh V. Halade

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Matrix Metalloproteinase-28 Deletion Exacerbates Cardiac Dysfunction and Rupture after Myocardial Infarction in Mice by Inhibiting M2 Macrophage Activation, Yonggang Ma, Ganesh V. Halade, Jianhua Zhang, Trevi A. Ramirez, Daniel Levin, Andrew Voorhees, Yu Fang Jin, Hai Chao Han, Anne M. Manicone, and Merry L. Lindsey

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Cardiac Wound Healing Post-Myocardial Infarction: a Novel Method to Target Extracellular Matrix Remodeling in the Left Ventricle, Rogelio Zamilpa, Jianhua Zhang, Ying Ann Chiao, Lisandra E. De Castro Brás, Ganesh V. Halade, Yonggang Ma, Sander O. Hacker, and Merry L. Lindsey

Submissions from 2012

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Dietary Coral Calcium and Zeolite Protects Bone in a Mouse Model for Postmenopausal Bone Loss, Jameela Banu, Erika Varela, Juan M. Guerra, Ganesh Halade, Paul J. Williams, Ali N. Bahadur, Kokichi Hanaoka, and Gabriel Fernandes

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Roles of Saturated Vs. Polyunsaturated Fat in Heart Failure Survival: Not All Fats Are Created Equal, Ganesh V. Halade, Yu Fang Jin, and Merry L. Lindsey

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Extracellular Matrix and Fibroblast Communication Following Myocardial Infarction, Yonggang Ma, Ganesh V. Halade, and Merry L. Lindsey

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Dha Derivatives of Fish Oil as Dietary Supplements: a Nutrition-Based Drug Discovery Approach for Therapies to Prevent Metabolic Cardiotoxicity, Yonggang Ma, Merry L. Lindsey, and Ganesh V. Halade

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Mathematical Modeling and Stability Analysis of Macrophage Activation in Left Ventricular Remodeling Post-Myocardial Infarction., Yunji Wang, Tianyi Yang, Yonggang Ma, Ganesh V. Halade, Jianqiu Zhang, Merry L. Lindsey, and Yu Fang Jin

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Transgenic Overexpression of Matrix Metalloproteinase-9 in Macrophages Attenuates the Inflammatory Response and Improves Left Ventricular Function Post-Myocardial Infarction, Rogelio Zamilpa, Jessica Ibarra, Lisandra E. de Castro Brás, Trevi A. Ramirez, Nguyen Nguyen, Ganesh V. Halade, Jianhua Zhang, Qiuxia Dai, Tariq Dayah, Ying Ann Chiao, Wesley Lowell, Seema S. Ahuja, Jeanine D'Armiento, Yu Fang Jin, and Merry L. Lindsey

Submissions from 2011

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Obesity-Mediated Inflammatory Microenvironment Stimulates Osteoclastogenesis and Bone Loss in Mice, Ganesh V. Halade, Amina El Jamali, Paul J. Williams, Roberto J. Fajardo, and Gabriel Fernandes

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Combination of Conjugated Linoleic Acid with Fish Oil Prevents Age-Associated Bone Marrow Adiposity in C57Bl/6J Mice, Ganesh V. Halade, Md M. Rahman, Paul J. Williams, and Gabriel Fernandes

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Fish Oil Decreases Inflammation and Reduces Cardiac Remodeling in Rosiglitazone Treated Aging Mice, Ganesh V. Halade, Paul J. Williams, Merry L. Lindsey, and Gabriel Fernandes

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Cassia Auriculata: Aspects of Safety Pharmacology and Drug Interaction, Amrutesh S. Puranik, Ganesh Halade, Sandeep Kumar, Ranjan Mogre, Kishori Apte, Ashok D.B. Vaidya, and Bhushan Patwardhan

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T10C12-Cla Maintains Higher Bone Mineral Density during Aging by Modulating Osteoclastogenesis and Bone Marrow Adiposity, Md M. Rahman, Ganesh V. Halade, Paul J. Williams, and Gabriel Fernandes

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Fish Oil Concentrate Delays Sensitivity to Thermal Nociception in Mice, Jyothi M. Veigas, Paul J. Williams, Ganesh Halade, Mizanur M. Rahman, Toshiyuki Yoneda, and Gabriel Fernandes

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Mathematical Modeling of Macrophage Activation in Left Ventricular Remodeling Post-Myocardial Infarction, Yunji Wang, Yufang Jin, Yonggang Ma, Ganesh V. Halade, and Merry L. Linsey

Submissions from 2010

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Differential Effects of Conjugated Linoleic Acid Isomers in Insulin-Resistant Female C57Bl/6J Mice, Ganesh V. Halade, Md M. Rahman, and Gabriel Fernandes

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Docosahexaenoic Acid-Enriched Fish Oil Attenuates Kidney Disease and Prolongs Median and Maximal Life Span of Autoimmune Lupus-Prone Mice, Ganesh V. Halade, Md Mizanur Rahman, Arunabh Bhattacharya, Jeffrey L. Barnes, Bysani Chandrasekar, and Gabriel Fernandes

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High Fat Diet-Induced Animal Model of Age-Associated Obesity and Osteoporosis, Ganesh V. Halade, Md M. Rahman, Paul J. Williams, and Gabriel Fernandes

Submissions from 2009

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Effect of Cla Isomers and Their Mixture on Aging C57Bl/6J Mice, Ganesh V. Halade, Md M. Rahman, and Gabriel Fernandes

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Conjugated Linoleic Acid (Cla) Prevents Age-Associated Skeletal Muscle Loss, Md M. Rahman, Ganesh V. Halade, Amina El Jamali, and Gabriel Fernandes

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The Fat-1 Transgene in Mice Increases Antioxidant Potential, Reduces Pro-Inflammatory Cytokine Levels, and Enhances Ppa Rγ and Sirt-1 Expression on a Calorie Restricted Diet, Md Mizanur Rahman, Ganesh V. Halade, Arunabh Bhattacharya, and Gabriel Fernandes

Submissions from 2007

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Anticonvulsant Effect of Origanum Majorana L., Dipti N. Deshmane, Chhaya H. Gadgoli, and Ganesh V. Halade