Doctor of Philosophy (Ph.D.)
Degree Granting Department
Cindy S. Tofthagen, Ph.D., ARNP
Susan C. McMillan, Ph.D., ARNP
Brent J. Small, Ph.D.
Carmen S. Rodriguez, Ph.D., ARNP
Chemotherapy Induced Peripheral Neuropathy, Neurotoxicity, assessment,, polyneuropathy, Patients’ Function
Chemotherapy Induced Peripheral Neuropathy (CIPN) is a common problem among cancer patients who receive a wide range of chemotherapy. This problem causes a decline in quality of life and increased disabilities. CIPN assessment instruments are either subjective, objective, or a combination of both. So far, there is no agreement on the best way for assessment. The goal of this study was to explore the relationships among subjective and objective CIPN assessment instruments. Specifically, this study aimed to 1) evaluate the relationship between the Total Neuropathy Score-reduced (mainly objective) and patients’ function, as measured by the interference scale of the Chemotherapy-Induced Peripheral Neuropathy Assessment Tool (subjective); and 2) evaluate the relationship between the Total Neuropathy Score-reduced and neuropathy symptom experience, as measured by the symptom experience scale of the Chemotherapy-Induced Peripheral Neuropathy Assessment Tool (Subjective). To achieve those aims, a secondary data analysis for 56 participants who participated in a study entitled: Group Acupuncture for Treatment of Neuropathy from Chemotherapy was done. After Pearson correlations were calculated, the study found that there is a positive, weak relationship between the TNSr and the symptom experience scale of the CIPNAT(r=0.34). A positive, week relationship was found between the TNSr and the interference with activity scale of the CIPNAT(r=0.28). These results suggest that objective and subjective assessment are not highly correlated, and likely measure different aspects of CIPN. A comprehensive assessment approach is needed for decision making in the clinical oncology setting.
Scholar Commons Citation
Abulhaija, Ashraf, "The Relationship Between Total Neuropathy Score-reduced, Neuropathy Symptoms and Function." (2017). Graduate Theses and Dissertations.