Graduation Year
2017
Document Type
Dissertation
Degree
Ph.D.
Degree Name
Doctor of Philosophy (Ph.D.)
Degree Granting Department
Chemistry
Major Professor
Xiaodong Shi, Ph.D.
Committee Member
Jianfeng Cai, Ph.D.
Committee Member
Kirpal Bisht, Ph.D.
Committee Member
Shengqian Ma, Ph.D.
Committee Member
Chuanhai Cao, Ph.D.
Keywords
Enyne cycloisomerization, Gold redox, Diazonium activation
Abstract
In this dissertation, gold catalyst was employed to catalyze intermolecular reactions. Intramolecular reactions were far more advanced than intermolecular reaction in gold catalysis. With finding suitable ligands for gold catalysts, we were able to develop several transformations to synthesize interesting building blocks in organic chemistry including: allenes, furans, spiros, oxepines, propargyl ethers and ketones. These functionalities were synthesized by the use of triazole-gold(I) catalyst. Triazole, as a ligand bond to gold, showed enhanced stability of the catalyst, which resulted in better yields. Gold(I)/(III) redox chemistry also used for cyclopropanol ring openings which resulted in synthesizing substituted ketones.
Scholar Commons Citation
Hosseyni, Seyedmorteza, "New Reaction Discoveries in Gold Catalysis" (2017). USF Tampa Graduate Theses and Dissertations.
https://digitalcommons.usf.edu/etd/6655
