Title

A Randomized Feasibility Pilot Trial of Hearing Treatment for Reducing Cognitive Decline: Results from the Aging and Cognitive Health Evaluation in Elders Pilot Study

Document Type

Article

Publication Date

2017

Keywords

Clinical trials, Cognition, Dementia, Epidemiology, Hearing, Longitudinal study, Memory, Presbycusis

Abstract

Introduction: Hearing loss (HL) is prevalent and independently related to cognitive decline and dementia. There has never been a randomized trial to test if HL treatment could reduce cognitive decline in older adults.

Methods: A 40-person (aged 70–84 years) pilot study in Washington County, MD, was conducted. Participants were randomized 1:1 to a best practices hearing or successful aging intervention and followed for 6 months. clinicaltrials.gov Identifier: NCT02412254.

Results: The Aging and Cognitive Health Evaluation in Elders Pilot (ACHIEVE-P) Study demonstrated feasibility in recruitment, retention, and implementation of interventions with no treatment-related adverse events. A clear efficacy signal of the hearing intervention was observed in perceived hearing handicap (mean of 0.11 to −1.29 standard deviation [SD] units; lower scores better) and memory (mean of −0.10 SD to 0.38 SD).

Discussion: ACHIEVE-P sets the stage for the full-scale ACHIEVE trial (N = 850, recruitment beginning November 2017), the first randomized trial to determine efficacy of a best practices hearing (vs. successful aging) intervention on reducing cognitive decline in older adults with HL.

Digital Object Identifier (DOI)

https://doi.org/10.1016/j.trci.2017.06.003

Citation / Publisher Attribution

Alzheimer's & Dementia: Translational Research & Clinical Interventions, v. 3, issue 3, p. 410-415

Was this content written or created while at USF?

Yes

Share

COinS