Nanorods Formed from a New Class of Peptidomimetics
Document Type
Article
Publication Date
9-7-2012
Digital Object Identifier (DOI)
https://doi.org/10.1021/ma3015992
Abstract
Although peptide amphiphiles have been explored as nanomaterials for different applications, nanostructures formed by hierarchical molecular assembly of sequence-specific peptidomimetics are much less developed. Such protein-like nanomaterials could enhance the current application of peptide-based amphiphiles by enriching the diversity of nanostructures, increasing in vivostability for biomedical applications, and facilitating the understanding of biomacromolecular self-assembly. Herein we present a biomimetic γ-AApeptide amphiphile which forms nanorods. Our results demonstrate the capability of γ-AApeptide amphiphiles as a potential scaffold for the preparation of biomimetic and bioinspired nanostructures. The programmability and biocompatibility of γ-AApeptides could lead to novel nanomaterials for a wide variety of applications.
Was this content written or created while at USF?
Yes
Citation / Publisher Attribution
Macromolecules, v. 45, issue 18, p. 7350–7355
Scholar Commons Citation
Niu, Youhong; Wu, Haifan; Huang, Rongfu; Qiao, Qiao; Costanza, Frankie; Wang, Xi-Sen; Hu, Yaogang; Amin, Mohamad Nassir; Nguyen, Anh-My; Zhang, James; Haller, Edward M.; Ma, Shengqian; Li, Xiao; and Cai, Jianfeng, "Nanorods Formed from a New Class of Peptidomimetics" (2012). Integrative Biology Faculty and Staff Publications. 273.
https://digitalcommons.usf.edu/bin_facpub/273
