Document Type
Patent
Publication Date
4-25-2017
Patent Number
9632076
CPC
G01N 33/5058 (20130101)
Abstract
This application provides devices for modeling ischemic stroke conditions. The devices can be used to culture neurons and to subject a first population of the neurons to low-oxygen conditions and a second population of neurons to normoxic conditions. The neurons are cultured on a porous barrier, and on the other side of the barrier run one or more fluid-filled channels. By flowing fluid with different oxygen levels through the channels, one can deliver desired oxygen concentrations to the cells nearest those channels.
Application Number
14/539,544
Recommended Citation
Achyuta, Anilkumar H.; Cuevas, Javier; Sundaram, Shivshankar; and Katnik, Chris, "Microfluidic device for generating neural cells to simulate post-stroke conditions" (2017). USF Patents. 924.
https://digitalcommons.usf.edu/usf_patents/924
Assignees
University of South Florida
Filing Date
2014-11-12
