A61K 31/5415 (20130101)
The subject invention concerns materials and methods for treating depression, stress disorders, such as PTSD, anxiety disorders, and/or a neurodegenerative disease or condition in a person or animal. In one embodiment, a person or animal in need of treatment is administered one or more compounds or drugs, or a composition comprising the one or more compounds or drugs, that inhibit FKBP51 activity or function. The subject invention also concerns a method for inhibiting activity of the FKBP51 protein in a cell. The subject invention also concerns methods of screening for compounds or drugs that inhibit the FKBP51 protein.
Sabbagh, Jonathan J. and Dickey, Chad, "Inhibitors of the FKBP51 protein from a high-throughput drug screen and methods of use" (2016). USF Patents. 880.
University of South Florida