A method is disclosed for treating and preventing diseases, wherein at least one of the causes of the disease is .beta.-amyloid peptide induced change in free radical production resulting in vascular endothelial dysfunction and vasoactivity, by antagonizing vascular free radicals in excess of functional equilibrium. An animal model for the disease is also disclosed.
Thomas, Thomas N.; Mullan, Michael; Arendash, Gary W.; Crawford, Fiona C.; and Suo, Zhiming, "Vasoactive effects and free radical generation by .beta.-amyloid peptides" (2000). USF Patents. 825.
University of South Florida