Method for elucidation and detection of polymorphisms, splice variants, and proximal coding mutations using intronic sequences of the alzheimer's S182 gene

Authors

John Hardy
Alison M. Goate

Document Type

Patent

Publication Date

July 2000

Patent Number

60836946

Abstract

A method of detecting polymorphisms in the S182 gene by detecting mutations in the S182 gene using selected mismatched PCR primers comprising sequences derived from intronic sequences of the S182 gene is provided. A method of identifying an individual susceptible to late onset Alzheimer's Disease is also provided.

Application Number

08/738,381

Recommended Citation

Hardy, John and Goate, Alison M., "Method for elucidation and detection of polymorphisms, splice variants, and proximal coding mutations using intronic sequences of the alzheimer's S182 gene" (2000). USF Patents. 818.
https://digitalcommons.usf.edu/usf_patents/818

Assignees

University of South Florida

Filing Date

10/25/1996

Primary/U.S. Class

435/6