Efficient carbamate synthesis

Authors

Kyung Woon Jung

Document Type

Patent

Publication Date

June 2002

Patent Number

6399808

Abstract

A method of preparing carbamates of the general formula RR’—N—CO₂—R” by reacting an amine with carbon dioxide and an organic electrophile in an anhydrous solvent in the presence of a cesium base, whereby carbamate synthesis is accomplished in good yield at mild temperatures, either in solution or on a solid support, and wherein R, R², and R” are hydrogen, alkyl of 1-18 carbon atoms, silyl, phenyl, benzyl, cyclopentyl, cyclohexyl, cycloheptyl, cyclooctyl, allyl, or heterocycle, which are widely used as industrial products, and as intermediates in organic synthesis.

Application Number

09/513,691

Recommended Citation

Jung, Kyung Woon, "Efficient carbamate synthesis" (2002). USF Patents. 787.
https://digitalcommons.usf.edu/usf_patents/787

Assignees

University of South Florida

Filing Date

02/25/2000

Primary/U.S. Class

560/19