Document Type
Patent
Publication Date
December 2015
Patent Number
9206131
CPC
C07D 215/233(20130101), C07D 215/42(20130101), C07D 215/60(20130101), C07D 239/90(20130101), C07D 279/16(20130101), C07D 401/04(20130101), C07D 401/06(20130101), C07D 401/12(20130101), C07D 403/04(20130101), C07D 403/06(20130101), C07D 413/04(20130101), C07D 491/052(20130101)
Abstract
Compounds of formula I:
or formula II:
or a pharmaceutically acceptable salt of formula I or formula II, wherein: R1 is H, hydroxyl, alkoxy, acyl, alkyl, cycloalkyl, aryl, or heteroaryl; R2 is methyl or haloalkyl; R4 is hydroxyl, carbonyloxy, or carbonyldioxy; and R3 is aliphatic, aryl, aralkyl, or alkylaryl; and R5, R6, R7 and R8 are each individually H, halogen, alkoxy, alkyl, haloalkyl, aryl, nitro, cyano, amino, amido, acyl, carboxyl, substituted carboxyl, or —SO2R10, wherein R10 is H, alkyl, amino or haloalkyl; provided that in formula I, R5 and R7 are not both H or R6 is not H or methoxy; and in formula II that if R4 is carbonyldioxy then R7 is not methoxy.
Application Number
14/055,757
Recommended Citation
Riscoe, Michael K.; Kelly, Jane X.; Winter, Rolf W.; Hinrichs, David J.; Smilkstein, Martin J.; Nilsen, Aaron; Burrows, Jeremy; Kyle, Dennis; Manetsch, Roman; Cross, Richard M.; Monastyrskyi, Andrii; and Flanigan, David L., "Compounds having antiparasitic or anti-infectious activity" (2015). USF Patents. 74.
https://digitalcommons.usf.edu/usf_patents/74
Assignees
Oregon Health & Science University
Filing Date
10/16/2013
