N-thiolated 2 oxazolidone antibiotics

Authors

Edward Turos
Rajesh Kumar Mishra

Document Type

Patent

Publication Date

February 2008

Patent Number

7332611

Abstract

This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class of anti bacterial agents. These compounds can be synthesized from 2-oxazolidinones by Ndeprotection and N-sulfenylation. These new substances were found to exhibit potent anti-bacterial activity, including bacteriostatic properties against Staphylococcus spp., including methicillin resistant Staphylcoccus aureus (MRSA), and Bacillus spp., including Bacillus anthracis.

Application Number

11/382,157

Recommended Citation

Turos, Edward and Mishra, Rajesh Kumar, "N-thiolated 2 oxazolidone antibiotics" (2008). USF Patents. 588.
https://digitalcommons.usf.edu/usf_patents/588

Assignees

University of South Florida

Filing Date

05/08/2006

Primary/U.S. Class

548/230