The invention disclosed herein provides for methods of treating cancer using inhibitors of the Raf/Mek/P-Erk 1/2 pathway. These inhibitors include B2AR agonists (such as ARA-211 (pirbuterol) and isoproterenol), adenylyl cyclase activators, cAMP analogs and Epac activators. The invention also provides methods for diagnosing cancer in an individual.
Sebti, Said M., "Inhibition of the Raf/Mek/P-Erk pathway for treating cancer" (2010). USF Patents. 485.
University of South Florida