The present invention is a method for early detection of cancer including the steps of identifying tissue from asymptomatic individuals, gathering a substantially homogenous cell population from the tissue by laser capture microdissection (LCM), analyzing the cell population with mass spectrometry and identifying predetermined peaks in the mass spectrometry associated with an overexpression of proteins in premalignant and malignant cells.
Zhukov, Tatyana A.; Tockman, Melvyn S.; and Johanson, Roy A., "Protein profiling for premalignant tissue" (2012). USF Patents. 330.
University of South Florida