The present invention provides a method of mediating hypo-activation of NK cells. Methods of the present invention comprise administering to a subject an effective amount of broad acting phosphotase inhibitor, such as sodium orthovanadate, SHP specific inhibitor. In one embodiment, the SHP specific inhibitor is NSC119910.
Wahle, Joseph and Kerr, William Garrow, "Method of activating NK cells" (2013). USF Patents. 202.
University of South Florida