Authors

George R. Simon

Document Type

Patent

Publication Date

April 2015

Patent Number

8999326

CPC

A61K 31/39(20130101), A61K 31/53(20130101)

Abstract

The subject invention concerns materials and methods for treating oncological disorders in a person or animal using any agent or compound that inhibits uptake of glucose into a cell. The subject invention also concerns methods for inducing apoptosis and inhibiting the proliferation or survival of a cell. In one embodiment, the methods comprise administering an effective amount of an agent or compound that inhibits the activity of one or more glucose transporter proteins, such as Glut-1. An antibody that binds to and inhibits a glucose transporter protein can be used in the present methods.

Application Number

12/673,677

Assignees

University of South Florida

Filing Date

08/15/2008

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