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Submissions from 2014

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Transport of thalidomide by the human intestinal caco-2 monolayers, Shufeng Zhou, Y Li, P Kestell, P Schafer, E Chan, and JW Paxton

Submissions from 2013

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The Effect of Somatostatin, Ulinastatin and Salvia miltiorrhiza on Severe Acute Pancreatitis Treatment, G Wang, J Wen, RR Wilbur, P Wen, SF Zhou, and X Xiao

Submissions from 2012

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Ligand- and protein-based modeling studies of the inhibitors of human cytochrome P450 2D6 and a virtual screening for potential inhibitors from the Chinese herbal medicine, Scutellaria baicalensis (Huangqin,Baikal Skullcap), SL Mo, WF Liu, Y Chen, HB Luo, LB Sun, XW Chen, ZW Zhou, KB Sneed, CG Li, YM Du, J Liang, and SF Zhou

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Cell therapy: a safe and efficacious therapeutic treatment for Alzheimer's disease in APP+PS1 mice, NR Nabar, F Yuan, X Lin, L Wang, G Bai, J Mayl, Y Li, SF Zhou, J Wang, J Cai, and C Cao

Submissions from 2006

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St. John's wort attenuates irinotecan-induced diarrhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosis, ZP Hu, XX Yang, SY Chan, AL Xu, W Duan, YZ Zhu, FS Sheu, UA Boelsterli, E Chan, Q Zhang, JC Wang, PL Ee, HL Koh, and M Huang

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Detection of aristolochic acid I, tetrandrine and fangchinoline in medicinal plants by high performance liquid chromatography and liquid chromatography/mass spectrometry, HL Koh, H Wang, Shufeng Zhou, E Chan, and SO Woo

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Pharmacokinetics of recombinant human endostatin in rats, XX Yang, ZP Hu, E Chan, W Duan, and S Zhou

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Monitoring drug-protein interaction, XX Yang, ZP Hu, SY Chan, and SF Zhou

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Drug-herb interactions: eliminating toxicity with hard drug design, XX Yang, ZP Hu, W Duan, YZ Zhu, and SF Zhou

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A mechanistic study on reduced toxicity of irinotecan by coadministered thalidomide, a tumor necrosis factor-alpha inhibitor, XX Yang, ZP Hu, AL Xu, W Duan, YZ Zhu, M Huang, FS Sheu, Q Zhang, JS Bian, E Chan, X Li, JC Wang, and SF Zhou

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The last 10 amino acid residues beyond the hydrophobic motif are critical for the catalytic competence and function of protein kinase Calpha, SS Yeong, Y Zhu, D Smith, C Verma, WG Lim, BJ Tan, QT Li, NS Cheung, M Cai, YZ Zhu, SF Zhou, SL Tan, and W Duan

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Reversal of resistance to oxazaphosphorines, J Zhang, Q Tian, YZ Zhu, AL Xu, and SF Zhou

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Clinical pharmacogenomics of thiopurine S-methyltransferase, Shufeng Zhou

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The very C-terminus of protein kinase Cepsilon is critical for the full catalytic competence but its hydrophobic motif is dispensable for the interaction with 3-phosphoinositide-dependent kinase-1, Y Zhu, D Smith, C Verma, WG Lim, BJ Tan, JS Armstrong, Shufeng Zhou, E Chan, SL Tan, YZ Zhu, NS Cheung, and W Duan

Submissions from 2005

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St. John's Wort modulates the toxicities and pharmacokinetics of CPT-11 (irinotecan) in rats, Z Hu, X Yang, PC Ho, E Chan, SY Chan, C Xu, X Li, YZ Zhu, W Duan, X Chen, M Huang, H Yang, and Shufeng Zhou

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Herb-drug interactions: a literature review, Z Hu, X Yang, PC Ho, SY Chan, PW Heng, E Chan, W Duan, HL Koh, and Shufeng Zhou

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Significant intestinal excretion, one source of variability in pharmacokinetics of COL-3, a chemically modified tetracycline, J Li, Shufeng Zhou, H Huynh, and E Chan

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Alteration of the pharmacokinetics of COL-3, a matrix metalloproteinase inhibitor, due to acute gastrointestinal toxicity of doxorubicin, J Li, Shufeng Zhou, H Huynh, W Duan, and E Chan

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Inhibition of human CYP1A2 oxidation of 5,6-dimethyl-xanthenone-4-acetic acid by acridines: a molecular modelling study, JW Paxton, P Kestell, D Chiang, Shufeng Zhou, and DF Lewis

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Human multidrug resistance associated protein 4 confers resistance to camptothecins, Q Tian, J Zhang, TM Tan, E Chan, W Duan, SY Chan, UA Boelsterli, PC Ho, H Yang, JS Bian, M Huang, YZ Zhu, W Xiong, and X Li

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Novel agents that potentially inhibit irinotecan-induced diarrhea, X Yang, Z Hu, SY Chan, E Chan, BC Goh, W Duan, and Shufeng Zhou

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Simultaneous determination of the lactone and carboxylate forms of irinotecan (CPT-11) and its active metabolite SN-38 by high-performance liquid chromatography: application to plasma pharmacokinetic studies in the rat, X Yang, Z Hu, SY Chan, BC Goh, W Duan, E Chan, and Shufeng Zhou

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Determination of thalidomide by high performance liquid chromatography: plasma pharmacokinetic studies in the rat, X Yang, Z Hu, SY Chan, PC Ho, E Chan, W Duan, BC Goh, and Shufeng Zhou

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Insights into oxazaphosphorine resistance and possible approaches to its circumvention, J Zhang, Q Tian, SY Chan, W Duan, and S Zhou

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Metabolism and transport of oxazaphosphorines and the clinical implications, J Zhang, Q Tian, S Yung Chan, S Chuen Li, Shufeng Zhou, W Duan, and YZ Zhu

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Effect of coenzyme Q10 on warfarin hydroxylation in rat and human liver microsomes, Q Zhou, Shufeng Zhou, and E Chan

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Effect of omeprazole on the hydroxylation of warfarin enantiomers in human: in-vitro studies with liver microsomes and cDNA-expressed cytochrome P450 isozymes, Q Zhou, Shufeng Zhou, and E Chan

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Drug bioactivation, covalent binding to target proteins and toxicity relevance, Shufeng Zhou, E Chan, W Duan, M Huang, and YZ Chen

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Transport of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid and its acyl glucuronide by human intestinal Caco-2 cells, Shufeng Zhou, X Feng, P Kestell, JW Paxton, BC Baguley, and E Chan

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Prediction of herb-drug metabolic interactions: a simulation study, Shufeng Zhou, M Huang, A Xu, H Yang, W Duan, and JW Paxton

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Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs, Shufeng Zhou, S Yung Chan, B Cher Goh, E Chan, W Duan, M Huang, and HL McLeod

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The PKCalpha-D294G mutant found in pituitary and thyroid tumors fails to transduce extracellular signals, Y Zhu, Q Dong, BJ Tan, WG Lim, Shufeng Zhou, and W Duan

Submissions from 2004

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Therapeutic drugs that behave as mechanism-based inhibitors of cytochrome P450 3A4, Shufeng Zhou, E Chan, LY Lim, UA Boelsterli, SC Li, J Wang, Q Zhang, M Huang, and A Xu

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Predicting pharmacokinetic herb-drug interactions, Shufeng Zhou, E Chan, SC Li, M Huang, X Chen, X Li, Q Zhang, and JW Paxton

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Pharmacokinetic interactions of drugs with St John's wort, Shufeng Zhou, E Chan, SQ Pan, M Huang, and EJ Lee

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Determination of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid and its acyl glucuronide in Caco-2 monolayers by liquid chromatography with fluorescence detection: application to transport studies, Shufeng Zhou, X Feng, P Kestell, BC Baguley, and JW Paxton

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Herbal bioactivation: the good, the bad and the ugly, Shufeng Zhou, HL Koh, Y Gao, ZY Gong, and EJ Lee

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Herbal modulation of P-glycoprotein, Shufeng Zhou, LY Lim, and B Chowbay