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Theses/Dissertations from 2020

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Hyaluronic Acid Coated Targeted Lipid Micellar Nanoparticle as a Delivery Vehicle for Lapatinib and Ketoconazole in EGFR mutated Lung Cancer, Nadia Tasnim Ahmed

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Structure Based Inhibitor Discovery Targeting Multiple β-Lactamases Involved in Antibiotic Resistance, Afroza Akhtar

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SSH1 Impedes p62/SQSTM1 Flux and Tau Clearance Independent of Cofilin Activation, Cenxiao Fang

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Testing Glutathione-S-Transferase Mu 1 (GSTM1) in Protecting Retinal Pigment Epithelium Cells from Oxidative Stress, Inyoung C. Garner

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Role of Thyroid Hormone Modulating Astrocyte Activation, Payal Ghosh

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Synthesis of a Targeted pH Responsive Nanoparticle for Controlled Release of Actinomycin D, Alejandro Jesus Gonzalez

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Discovery and Characterization of Small Molecule Inhibitors of Bromodomains, Md Rezaul Karim

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Targeting Cancer-Anorexia Cachexia Syndrome and Septic Inflammatory-Based Atrophy With R/S 1,3 Butanediol Acetoacetate Diester, Andrew P. Koutnik

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Cognition in Health and Disease: Two Mouse Model Studies, Heather Lynn Mahoney

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Functional Significance of Endothelial Sigma-1 Receptors in Vascular Reactivity and Barrier Function, Zeinab Y. Motawe

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Mass Spectrometry Discovery-Based Proteomics to Examine Anti-Aging Effects of the Nutraceutical NT-020 in Rat Serum, Samantha M. Portis

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Dendriplex - Cyclodextrin conjugates for Gene delivery to Retina, Durga Deepak Puro

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Immune Modulation as a Therapeutic Target in an α-synuclein Model of Parkinson’s Disease, Meena Subhashini Subbarayan

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Role of Serum Amyloid P Component in the Pathogenesis of Chronic Traumatic Encephalopathy, Brittany Urban

Theses/Dissertations from 2017

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Receptor-Associated Protein (RAP) Models In Vivo Reelin Haploinsufficiency: Implications in Schizophrenia, Jamileh Ahmed

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The Potential Role of Antiretroviral Efavirenz in HIV Associated Neurocognitive Disorders, Lecia Ashanna Moya Brown

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The Role of Elevated Hyaluronan-Mediated Motility Receptor (RHAMM/HMMR) in Ovarian Cancer, Stephanie T. Buttermore

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Mass-spectrometry Based Proteomics of Age-related Changes in Murine Microglia, Antwoine Flowers

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Astaxanthin Attenuates MPTP Induced Neurotoxicity and Modulates Cognitive Function in Aged Mice, Beth Grimmig

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Microfluidic Biopsy Trapping Device for the Real-time Monitoring of the Tumor Microenvironment, Angela Holton

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Identifying New Treatment Options and Risk Factors for Type 2 Diabetes: The Potential Role of Thymoquinone and Persistent Organic Pollutants, Shpetim Karandrea

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Acetaminophen Associated Neurotoxicity and its Relevance to Neurodevelopmental Disorders, Seol-Hee Kim

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Synthesis, in vitro Characterization and Applications of Novel 8-Aminoquinoline Fluorescent Probes, Adonis McQueen

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Role of Amylase in Ovarian Cancer, Mai Mohamed

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Computational Analysis of Protein Intrinsic Disorder in Human Diseases, Insung Na

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Mechanism Elucidation and Inhibitor Discovery against Serine and Metallo-Beta-Lactamases Involved in Bacterial Antibiotic Resistance, Orville A. Pemberton

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osteopontin plays a pivotal role in in increasing severity of respiratory syncytial virus infection, Viviana Sampayo-Escobar

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Tau-Directed Immunotherapy for Alzheimer’s Disease, Sulana Kay Schroeder

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Therapeutic Modulation of Cancer Metabolism with Dichloroacetate and Metformin, Nathan Patrick Ward

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Acute Kidney Injury and Chronic Kidney Disease, Jin Wei

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Regulation of Extracellular Signal-Regulated Kinase by Histone Deacetylase 6, Jheng-Yu Wu

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Glomerular Hyperfiltration and Hypertension in Diabetes, Jie Zhang

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S1P-Mediated Endothelial Barrier Enhancement: Role of Rho Family GTPases and Local Lamellipodia, Xun E. Zhang

Theses/Dissertations from 2016

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Antimalarial Exoerythrocytic Stage Drug Discovery and Resistance Studies, Lynn Dong Blake

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Respiratory Syncytial Virus-infected Mesenchymal Stem Cells Regulate Immunity via Interferon-beta and Indoleamine-2,3-dioxygenase, Michael B. Cheung

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Hypercapnic Hyperoxia Increases Free Radical Production and Cellular Excitability in Rat Caudal Solitary Complex Brain Slice Neurons, Geoffrey Edward Ciarlone

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The Effects of Synthetic and Dietary Therapeutics on Learning, Memory, Motor Coordination, and Seizure in an Angelman Syndrome Mouse Model, Stephanie Lynn Ciarlone

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Leukemia Inhibitory Factor as a Neuroprotective Agent against Focal Cerebral Ischemia, Stephanie Davis

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Intrinsic Disorder Where You Least Expect It: The Incidence and Functional Relevance of Intrinsic Disorder in Enzymes and the Protein Data Bank, Shelly Deforte

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Sialylation and Cardiomyocyte Complex N -Glycosylation Protect Against Dilated Cardiomyopathy and Heart Failure, Wei Deng

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The Effects of Phytohormones and Isoprenoids in Dihydroartemisinin-induced Dormancy in the Erythrocytic Stages of Plasmodium falciparum, Marvin Duvalsaint Duvalsaint

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Antigen Specific Induced T Regulatory Cellular Therapy for Graft-Versus-Host Disease Following Allogeneic Bone Marrow Transplantation, Jessica Lauren Heinrichs

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Cardiovascular Effects Evoked by Airway Nociceptive Reflexes in Healthy and Cardiovascular Diseased Rats, Justin Shane Hooper

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Contribution of Epithelial Hypoxia Signaling to Pulmonary Fibrosis: Role of FAK1 and Galectin-1 as Driver Molecules, Jaymin J. Kathiriya

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Metabolic Therapy for Age-Dependent Impaired Wound Healing, Shannon Lynn Kesl

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A Caenorhabditis elegans Model to Detect Developmental Teratogens with Adverse Reproductive and Metabolic Effects, Alexis Ann Killeen

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The Concerted Regulation of Intracellular Signaling by Amyloid Precursor Protein and Aβ Peptide, Lisa Kirouac

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Significance of PTEN Phosphorylation and its Nuclear Function in Lung Cancer, Prerna Malaney

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Targeting Tau Degradation by Small Molecule Inhibitors for Treatment of Tauopathies, Mackenzie Martin

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Graphene Quantum Dots-Based Drug Delivery for Ovarian Cancer Therapy, Yiru Qin

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Regulation of Palmitoylation Enzymes and Substrates by Intrinsically Disordered Regions, Krishna D. Reddy

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Mitochondrial Heteroplasmy Contributes to the Dynamic Atovaquone Resistance Response in Plasmodium falciparum, Sasha Victoria Siegel

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Inhibiting the Interaction Between Grp94 and Myocilin to Treat Primary Open-Angle Glaucoma, Andrew Stothert

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Cardiovascular regulation by Kvβ1.1 subunit, Jared Tur