Document Type

Article

Publication Date

1-1-2013

Keywords

Comorbidity, cardiovascular

Digital Object Identifier (DOI)

http://dx.doi.org/10.1155/2013/563246

Abstract

Background. Everything known about the roles, relationships, and repercussions of comorbidity in cardiovascular disease is shaped by how comorbidity is currently measured.

Objectives. To critically examine how comorbidity is measured in randomized controlled trials or clinical trials and prospective observational studies in acute myocardial infarction (AMI), heart failure (HF), or stroke.

Design. Systematic review of studies of hospitalized adults from MEDLINE CINAHL, PsychINFO, and ISI Web of Science Social Science databases. At least two reviewers screened and extracted all data.

Results. From 1432 reviewed abstracts, 26 studies were included (AMI n = 8, HF n = 11, stroke n = 7). Five studies used an instrument to measure comorbidity while the remaining used the presence or absence of an unsubstantiated list of individual diseases. Comorbidity data were obtained from 1–4 different sources with 35% of studies not reporting the source. A year-by-year analysis showed no changes in measurement.

Conclusions. The measurement of comorbidity remains limited to a list of conditions without stated rationale or standards increasing the likelihood that the true impact is underestimated.

Comments

This article was written while the author, Harleah G. Buck, was at a previous institution.

Rights Information

Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.

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Citation / Publisher Attribution

Nursing Research and Practice, v. 2013, article ID 563246, p. 1-11.

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