Graduation Year

2005

Document Type

Thesis

Degree

M.S.

Degree Granting Department

Physics

Major Professor

Wei Chen (Ph.D.).

Keywords

Liquid chromatography, Human skin, Skin conductance, Benadryl, Diphenhydramine hydrochloride

Abstract

Although an iontophoretic trans-dermal drug delivery is known as an effective means for drug transportation through the human skin, it is not widely used because of the various side effects that come to life due to a high applied voltage of up to 80V.This study introduces an alternative means of drug transportation through the skin by means of sweat gland activation and reduction of an applied voltage to ensure that the iontophoresis is safe.

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