Degree Granting Department
Dr. Cheryl Kirstein.
Development, Adolescent, Dopamine, Novelty-seeking, Impulsivity, Neurochemistry, Nucleus accumbens
Adolescence is a time of high risk behavior and increased exploration. This developmental period is marked by a greater probability to initiate drug use and is associated with an increased risk to develop addiction and dependency in adulthood. Human adolescents are predisposed toward an increased likelihood of risk taking behaviors (Zuckerman M, 1986), including drug use or initiation. The purpose of this study was to examine differences in developmental risk taking behaviors and neurochemical responsivity to cocaine based on these behavioral characteristics. Adolescent and adult animals were exposed to a novel stimulus in a familiar environment to assess impulsivity, novelty preference and exploratory behaviors, subsequently, in vivo microdialysis was performed to assess dopaminergic responsivity to cocaine.
Scholar Commons Citation
Stansfield, Kirstie Helen, "Neurochemical analysis of cocaine in adolescence and adulthood" (2005). Graduate Theses and Dissertations.